Analytical Data
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Gene name
HNRNPK
- Application
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Alternative Names
Transformation up-regulated nuclear protein ;TUNP
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Species
Human
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Source
E. coli
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Tag
N- GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P61978
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Expression Region
3-464aa
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Molecular Weight
78.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
HNRNPK, or heterogeneous nuclear ribonucleoprotein K, is a multifunctional protein that plays a critical role in various cellular processes, including RNA processing, splicing, and regulation of gene expression. Its involvement in mRNA metabolism and interaction with various RNA species makes it essential for maintaining cellular homeostasis. Additionally, HNRNPK has been implicated in several pathological conditions, including cancer, where it can influence tumor progression and response to therapy. The protein predominantly resides in the nucleus but can also shuttle between the nucleus and cytoplasm, highlighting its role in post-transcriptional regulation. Given its importance in both normal cellular function and disease pathogenesis, the study of recombinant HNRNPK protein has gained traction. Researchers aim to understand its structure-function relationships, post-translational modifications, and interactions with RNA and other proteins. Moreover, exploring the biochemical properties and functional implications of HNRNPK can reveal potential therapeutic targets for diseases where its dysregulation is a contributing factor. Therefore, the investigation of recombinant HNRNPK not only enhances our understanding of its biological roles but also opens avenues for developing novel strategies to manipulate its function in disease contexts.
