Analytical Data
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Gene name
ISX
- Application
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Alternative Names
RAX-like homeobox
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Species
Human
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Source
E. coli
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Tag
N- His-SUMO
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q2M1V0
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Expression Region
1-245aa
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Molecular Weight
43 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ISX (Intestinal Specific Homeobox) is a transcription factor that plays a crucial role in the regulation of intestinal mucosal biology and immune responses. Research into ISX has gained momentum due to its significant implications for understanding various gastrointestinal disorders, including inflammatory bowel disease (IBD) and colorectal cancer. Disruptions in ISX expression can lead to altered intestinal barrier function and dysregulation of immune responses, contributing to mucosal inflammation. The study of ISX and its associated signaling pathways aims to uncover novel therapeutic targets for enhancing gut health and developing treatments for related diseases. Moreover, the ability to produce recombinant ISX proteins has advanced our understanding of its functional mechanisms. Researchers are focused on characterizing these recombinant proteins to elucidate their roles in cell differentiation, immune modulation, and maintaining the intestinal epithelium. This research not only enhances our knowledge of intestinal biology but also opens new avenues for the development of strategies aimed at promoting gut integrity and preventing disease. As a result, ISX is emerging as a promising biomarker and therapeutic target in gastrointestinal health and disease management.
