Analytical Data
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Gene name
NCBP2
- Application
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Alternative Names
20KDA nuclear cap-binding protein Cell proliferation-inducing gene 55 protein NCBP 20KDA subunit
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Species
Human
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Source
E. coli
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Tag
N- GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P52298
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Expression Region
2-156aa
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Molecular Weight
44.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
NCBP2 (Nuclear Cap Binding Protein 2) is an essential component of the nuclear cap-binding complex that plays a crucial role in RNA metabolism, including transcription, RNA processing, and export. Its involvement in cellular processes such as mRNA stabilization and translation initiation highlights its significance in gene expression regulation. Research into NCBP2 has gained momentum due to its potential implications in various diseases, particularly cancers and genetic disorders, where aberrant RNA processing can lead to pathological outcomes. The recombinant expression of NCBP2 allows for detailed studies of its structural and functional properties, enabling scientists to explore its interaction with other cellular molecules and its role in the cellular environment. By producing NCBP2 in a controlled system, researchers can investigate its biophysical characteristics, identify binding partners, and elucidate its mechanism of action. The study of NCBP2, particularly through recombinant protein techniques, has thus become a focal point in molecular biology and therapeutic research, paving the way for novel insights into RNA biology and potential therapeutic targets.
