Analytical Data
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Gene name
OGFR
- Application
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Alternative Names
OGFr (Protein 7-60) (Zeta-type opioid receptor)
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Species
Human
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Source
E. coli
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Tag
N- His & C- Myc
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9NZT2
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Expression Region
1-677aa
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Molecular Weight
80.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The research on the recombinant protein of the Opioid Growth Factor Receptor (OGFR) has gained significant attention due to its pivotal role in modulating various physiological and pathological processes. OGFR is a G protein-coupled receptor primarily known for its interaction with the opioid growth factor, which is involved in regulating cell proliferation, differentiation, and apoptosis across various tissues. The understanding of OGFR's functions extends to its implications in pain management, neuroprotection, and cancer biology, making it a target of interest for therapeutic interventions. recombinant OGFR proteins facilitate enhanced characterization of receptor properties, signaling pathways, and ligand interactions, thereby providing insights into its biological functions. Moreover, the development of OGFR as a potential biomarker for certain diseases and its influence on opioid signaling pathways can pave the way for new treatment strategies that mitigate addiction while maximizing therapeutic efficacy. The production of recombinant OGFR proteins also holds significance in structure-function studies and drug discovery, ultimately contributing to advancements in translational medicine and pharmacology. As research continues, the influence of OGFR in mental health, metabolic disorders, and other areas of concern is likely to uncover novel avenues for clinical application, underscoring the importance of this receptor in contemporary biomedical research.
