Analytical Data
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基因名
NTF4
- Application
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别名
Neurotrophin-5 ;NT-5Neutrophic factor 4
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种属
Human
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表达系统
E. coli
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P34130
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表达区间
82-210aa
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分子量
17.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
NTF4, or Neurotrophin-4, is a member of the neurotrophin family, which plays a crucial role in the growth, survival, and differentiation of neurons in the nervous system. As a neurotrophic factor, NTF4 is primarily involved in the maintenance of sympathetic and sensory neurons, influencing various pathways that impact nerve function. Research on NTF4 has garnered significant attention due to its potential therapeutic applications for neurodegenerative diseases and nerve injuries. Recombinant NTF4 proteins have been developed for in vitro and in vivo studies to elucidate their biological functions, promote neuronal survival, and facilitate regeneration processes. Scientists have been focusing on characterizing the molecular mechanisms underlying NTF4 signaling and its interaction with TrkB and p75NTR receptors. Moreover, investigating NTF4’s role in synaptic plasticity and its effects on cognition has opened new avenues for understanding neurological disorders, including depression and Alzheimer's disease. The production of recombinant NTF4 has enabled high-throughput screening for small molecules that can modulate its activity, potentially leading to novel therapeutic strategies. Overall, NTF4 research holds promise for advancing neurobiology and developing innovative treatments for various neurological conditions, making it a significant area of focus within the field of biomedical research.
