Analytical Data
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基因名
Nr5a2
- Application
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别名
Liver receptor homolog 1 (LRH-1) (Lrh1)
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种属
Mouse
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表达系统
E. coli
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标签
N- His & C- Myc
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P45448
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表达区间
1-560aa
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分子量
71.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Nr5a2, also known as Liver Receptor Homolog-1 (LRH-1), is a nuclear receptor that plays a crucial role in various biological processes, including endocrine regulation, liver development, and metabolism. It is involved in the expression of genes related to lipid metabolism, steroidogenesis, and glucose homeostasis, making it a significant target in understanding metabolic diseases and liver disorders. Research has shown that Nr5a2 is essential for the maintenance of pancreatic beta-cell function and plays a protective role in the progression of diabetes. Recent studies have focused on generating recombinant Nr5a2 protein to elucidate its structure-function relationship and regulatory mechanisms. The production of Nr5a2 as a recombinant protein allows for in-depth biochemical assays and the exploration of its interactions with other proteins and ligands. This research holds promise for developing therapeutic strategies for metabolic disorders and advancing our understanding of nuclear receptor signaling pathways. As we continue to investigate the implications of Nr5a2 in health and disease, recombinant protein studies are instrumental in revealing potential drug targets and treatment avenues for related conditions.
