Analytical Data
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基因名
SERPINE2
- Application
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别名
Peptidase inhibitor 7 Short name: PI-7 Protease nexin 1 Short name: PN-1 Protease nexin I Serpin E2
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种属
Human
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表达系统
E. coli
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标签
N- His-SUMO
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P07093
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表达区间
20-398aa
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分子量
57.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SERPINE2, also known as Neuroserpin, is a member of the serine protease inhibitor family, primarily expressed in the central nervous system. Its main function is to regulate proteolytic enzymes, playing a critical role in neuroprotection and synaptic plasticity. Dysregulation of SERPINE2 has been implicated in various neurodegenerative diseases, including Alzheimer's disease and traumatic brain injury, where it may contribute to neuronal damage and inflammation. Researchers have been focusing on the recombinant production of SERPINE2 to explore its biological functions in greater detail and assess its potential as a therapeutic target. The ability to produce this protein in large quantities allows for structural and functional studies, which contribute to our understanding of its role in neuronal health and disease. Moreover, the development of SERPINE2 as a biomarker or therapeutic agent could provide novel interventions for neurological disorders. As such, studying recombinant SERPINE2 is pivotal for advancing our knowledge in neurobiology and developing new strategies for tackling neurodegenerative diseases.












