Analytical Data
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基因名
BACH2
- Application
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别名
(BTB and CNC homolog 2)
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种属
Human
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表达系统
E. coli
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BYV9
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表达区间
618-770aa
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分子量
23.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
BACH2, a member of the BACH transcription factor family, plays a critical role in the regulation of immune responses, particularly in B cell differentiation and function. Research has shown that BACH2 is vital for the development of regulatory T cells and the maintenance of tolerance, making it an important focus in immunological studies. Its dysregulation is associated with various autoimmune diseases and malignancies, suggesting that BACH2 could serve as a potential therapeutic target. The study of recombinant BACH2 protein is crucial for understanding its functional mechanisms, providing insights into its role in transcriptional regulation and protein interactions in immune cells. Utilizing recombinant DNA technology, scientists can express and purify BACH2 proteins for functional assays, structural studies, and the exploration of its interactions with other proteins involved in immune signaling pathways. This research not only enhances our understanding of the molecular pathways governed by BACH2 but also paves the way for developing targeted treatments for diseases linked to immune dysregulation. By elucidating the biological significance of BACH2 through recombinant protein studies, researchers aim to unlock new potential avenues for therapeutic intervention in autoimmune disorders and cancers characterized by BACH2 abnormalities.
