Analytical Data
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基因名
WNT16
- Application
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别名
WNT16；Protein Wnt-16
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UBV4
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表达区间
30-365aa
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氨基酸序列
N WMWLGIASFG VPEKLGCANL PLNSRQKELC KRKPYLLPSI REGARLGIQE CGSQFRHERW NCMITAAATT APMGASPLFG YELSSGTKET AFIYAVMAAG LVHSVTRSCS AGNMTECSCD TTLQNGGSAS EGWHWGGCSD DVQYGMWFSR KFLDFPIGNT TGKENKVLLA MNLHNNEAGR QAVAKLMSVD CRCHGVSGSC AVKTCWKTMS SFEKIGHLLK DKYENSIQIS DKTKRKMRRR EKDQRKIPIH KDDLLYVNKS PNYCVEDKKL GIPGTQGREC NRTSEGADGC NLLCCGRGYN THVVRHVERC ECKFIWCCYV RCRRCESMTD VHTCK
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
WNT16 is a member of the Wnt signaling pathway, which plays a crucial role in various biological processes, including cell proliferation, differentiation, and tissue homeostasis. Research has indicated that WNT16 is involved in bone development and remodeling, making it a significant factor in the context of osteoporosis and other bone-related diseases. Studies have shown that variations in the WNT16 gene can influence bone mineral density and susceptibility to fractures. Given its potential implications in skeletal disorders, the recombinant WNT16 protein has garnered attention for its application in therapeutic strategies aimed at enhancing bone health. Exploration of WNT16 functions and mechanisms may unveil new insights into bone biology, providing avenues for developing novel treatments for osteoporosis and other conditions characterized by compromised bone strength. Understanding the structure and activity of WNT16 in vitro could also facilitate the discovery of small molecules or biologics that modulate its signaling pathways, paving the way for innovative approaches to bone regeneration and repair. Overall, the research surrounding recombinant WNT16 protein holds promise for advancing our knowledge of bone metabolism and developing targeted therapies to combat bone-related diseases.
