Analytical Data
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基因名
WNT2
- Application
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别名
WNT2；INT1L1；IRP；Protein Wnt-2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P09544
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表达区间
1-360aa
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氨基酸序列
MNAPLGGIWLWLPLLLTWLTPEVNSSWWYMRATGGSSRVMCDNVPGLVSS QRQLCHRHPDVMRAISQGVAEWTAECQHQFRQHRWNCNTLDRDHSLFGRV LLRSSRESAFVYAISSAGVVFAITRACSQGEVKSCSCDPKKMGSAKDSKG IFDWGGCSDNIDYGIKFARAFVDAKERKGKDARALMNLHNNRAGRKAVKR FLKQECKCHGVSGSCTLRTCWLAMADFRKTGDYLWRKYNGAIQVVMNQDG TGFTVANERFKKPTKNDLVYFENSPDYCIRDREAGSLGTAGRVCNLTSRG MDSCEVMCCGRGYDTSHVTRMTKCGCKFHWCCAVRCQDCLEALDVHTCKA PKNADWTTAT
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分子量
65 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
WNT2 is a member of the Wnt signaling pathway, which plays a critical role in various biological processes, including embryonic development, cell proliferation, and differentiation. Dysregulation of WNT signaling has been implicated in numerous diseases, particularly in cancer, where it can contribute to tumorigenesis and metastasis. Research into WNT2 recombinant protein has gained traction due to its potential therapeutic applications, particularly in regenerative medicine and cancer treatment. Recombinant WNT2 protein can be utilized to study its precise role in cellular signaling pathways, offering insights into its mechanism of action and biological effects. Additionally, understanding the interactions between WNT2 and its receptors can lead to the development of targeted therapies designed to modulate Wnt signaling in pathological conditions. This approach holds promise for enhancing tissue regeneration, inhibiting tumor growth, and improving patient outcomes in various malignancies. Moreover, WNT2 has been found to influence stem cell behavior and differentiation, positioning it as a critical factor in tissue engineering and regenerative applications. Overall, the investigation of WNT2 recombinant protein serves as a pivotal point in elucidating the complexities of Wnt signaling and its implications for both health and disease.
