Analytical Data
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基因名
CD1e
- Application
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别名
CD1e;T-cell surface glycoProtein CD1e. membrane-associated
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P15812
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表达区间
30-305aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSEEQLSFR MLQTSSFANH SWAHSEGSGW LGDLQTHGWD TVLGTIRFLK PWSHGNFSKQ ELKNLQSLFQ LYFHSFIQIV QASAGQFQLE YPFEIQILAG CRMNAPQIFL NMAYQGSDFL SFQGISWEPS PGAGIRAQNI CKVLNRYLDI KEILQSLLGH TCPRFLAGLM EAGESELKRK VKPEAWLSCG PSPGPGRLQL VCHVSGFYPK PVWVMWMRGE QEQRGTQRGD VLPNADETWY LRATLDVAAG EAAGLSCRVK HSSLGGHDLI IHWGGYS
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分子量
33 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CD1e is a member of the CD1 family of glycoproteins, which play a crucial role in the immune system by presenting lipid and glycolipid antigens to T cells. Unlike classical major histocompatibility complex (MHC) molecules that present peptide antigens, CD1 molecules, including CD1e, are specialized in the presentation of non-peptidic antigens, making them essential for recognizing microbial lipids, self-lipids, and other lipid-based antigens. The study of CD1e is particularly important because it is involved in the activation of specific subsets of T cells, such as invariant natural killer T (iNKT) cells, which have been linked to various immune responses, including anti-tumor immunity and responses to infections. Research on CD1e recombination protein has gained momentum as scientists aim to better understand its structure, function, and the molecular mechanisms underlying its interactions with lipids and T cell receptors. This knowledge could pave the way for developing novel immunotherapies and vaccines, potentially enhancing the ability to manipulate the immune response for therapeutic purposes. Additionally, exploring CD1e's role in autoimmune diseases and infections could provide insights into its contribution to various pathological states, revealing targets for intervention and treatment strategies. Overall, the investigation of CD1e recombined protein serves as a promising frontier in immunology, bridging gaps in our understanding of lipid antigen presentation and its implications for health and disease.












