Analytical Data
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Gene name
CD207
- Application
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Alternative Names
CD207；CLEC4K；C-type lectin domain family 4 member K
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9UJ71
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Expression Region
65-328aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSPRFMGTI SDVKTNVQLL KGRVDNISTL DSEIKKNSDG MEAAGVQIQM VNESLGYVRS QFLKLKTSVE KANAQIQILT RSWEEVSTLN AQIPELKSDL EKASALNTKI RALQGSLENM SKLLKRQNDI LQVVSQGWKY FKGNFYYFSL IPKTWYSAEQ FCVSRNSHLT SVTSESEQEF LYKTAGGLIY WIGLTKAGME GDWSWVDDTP FNKVQSARFW IPGEPNNAGN NEHCGNIKAP SLQAWNDAPC DKTFLFICKR PYVPSEP
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Molecular Weight
32 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CD207, also known as Langerin, is a type II transmembrane protein predominantly expressed on Langerhans cells, which are specialized antigen-presenting cells found in the skin and mucosal tissues. It plays a crucial role in the immune system by facilitating the capture and processing of antigens, particularly those derived from pathogens. The significance of CD207 lies in its ability to form a dendritic network within the epidermis, where it directs the immune response and influences tolerance and immunity. Research on CD207 recombinant protein has garnered attention due to its potential applications in immunotherapy, particularly in developing vaccines and therapeutic strategies against various infections and cancers. By producing CD207 as a recombinant protein, scientists aim to study its structural and functional characteristics, understand its role in antigen presentation, and evaluate its applications in enhancing immune responses. Furthermore, understanding the interactions between CD207 and pathogens could lead to novel approaches for treating diseases characterized by dysfunctional immune responses. Overall, the study of CD207 recombinant protein provides insights into immune regulation and holds promise for advancing therapeutic interventions.
