Analytical Data
-
基因名
AQP2
- Application
-
别名
AQP2；Aquaporin-2
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
P41181
-
表达区间
1-271aa
-
氨基酸序列
MWELRSIAFSRAVFAEFLATLLFVFFGLGSALNWPQALPSVLQIAMAFGL GIGTLVQALGHISGAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAG AALLHEITPADIRGDLAVNALSNSTTAGQAVTVELFLTLQLVLCIFASTD ERRGENPGTPALSIGFSVALGHLLGIHYTGCSMNPARSLAPAVVTGKFDD HWVFWIGPLVGAILGSLLYNYVLFPPAKSLSERLAVLKGLEPDTDWEERE VRRRQSVELHSPQSLPRGTKA
-
分子量
55 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Aquaporin-2 (AQP2) is a water channel protein primarily expressed in the kidney, playing a crucial role in the regulation of water reabsorption in the collecting ducts. Its function is vital for maintaining body fluid homeostasis and urine concentration. Dysfunction or altered expression of AQP2 is associated with various renal and endocrine disorders, such as nephrogenic diabetes insipidus and heart failure. The study of recombinant AQP2 proteins has gained attention as it allows researchers to explore the protein's structure, function, and interaction mechanisms in detail. By expressing AQP2 in heterologous systems, scientists can produce large quantities of the protein, facilitating biochemical assays and structural analyses that highlight how AQP2 operates within cellular membranes. Moreover, investigations into AQP2 variants and their trafficking, regulation by hormones, and pharmacological modulation can pave the way for novel therapeutic strategies. Overall, the focus on AQP2 recombinant proteins is pivotal for understanding kidney physiology and developing treatments for water balance disorders.
