Analytical Data
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基因名
NPY2R
- Application
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别名
NPY2R；Neuropeptide Y receptor type 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P49146
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表达区间
1-381aa
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氨基酸序列
MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQ VVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVN TLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHR CIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEI VACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHV SPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDL KEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIH SEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
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分子量
69 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
NPY2R (Neuropeptide Y receptor Y2) is a G-protein-coupled receptor that plays a crucial role in regulating various physiological processes, including appetite control, energy homeostasis, and neuroendocrine functions. The interest in NPY2R has grown due to its involvement in obesity, anxiety, and depression, making it a potential target for therapeutic interventions. Research indicates that NPY2R mediates the effects of neuropeptide Y (NPY), which is a neurotransmitter involved in stimulating food intake and promoting fat storage. Understanding the structure and function of NPY2R can provide valuable insights into its mechanistic role in these pathways. The expression of recombinant NPY2R proteins allows researchers to study the receptor's pharmacological properties, signaling mechanisms, and interactions with ligand molecules, thereby aiding in drug discovery efforts. Investigating the receptor's behavior in different cellular contexts can lead to the identification of novel therapeutic compounds that can modulate NPY2R activity, potentially offering new strategies for treating metabolic and mood disorders. Overall, the study of NPY2R recombinant proteins is pivotal for elucidating the biological roles of this receptor and developing innovative treatment approaches in the context of related diseases.
