Analytical Data
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Gene name
NPY2R
- Application
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Alternative Names
NPY2R；Neuropeptide Y receptor type 2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P49146
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Expression Region
1-381aa
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AA Sequence
MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQ VVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVN TLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHR CIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEI VACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHV SPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDL KEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIH SEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
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Molecular Weight
69 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
NPY2R (Neuropeptide Y receptor Y2) is a G-protein-coupled receptor that plays a crucial role in regulating various physiological processes, including appetite control, energy homeostasis, and neuroendocrine functions. The interest in NPY2R has grown due to its involvement in obesity, anxiety, and depression, making it a potential target for therapeutic interventions. Research indicates that NPY2R mediates the effects of neuropeptide Y (NPY), which is a neurotransmitter involved in stimulating food intake and promoting fat storage. Understanding the structure and function of NPY2R can provide valuable insights into its mechanistic role in these pathways. The expression of recombinant NPY2R proteins allows researchers to study the receptor's pharmacological properties, signaling mechanisms, and interactions with ligand molecules, thereby aiding in drug discovery efforts. Investigating the receptor's behavior in different cellular contexts can lead to the identification of novel therapeutic compounds that can modulate NPY2R activity, potentially offering new strategies for treating metabolic and mood disorders. Overall, the study of NPY2R recombinant proteins is pivotal for elucidating the biological roles of this receptor and developing innovative treatment approaches in the context of related diseases.
