Analytical Data
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Gene name
ND75
- Application
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Alternative Names
Complex I-75kD Short name: CI-75kD
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Species
Drosophila melanogaster
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Source
E. coli
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Tag
N- His-SUMO
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q94511
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Expression Region
28-315aa
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Molecular Weight
47.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ND75 recombinant protein is derived from the ND75 gene, which plays a crucial role in various cellular processes, particularly in the regulation of mitochondrial function and energy metabolism. Research into ND75 has gained traction due to its potential implications in cellular respiration, oxidative stress response, and signaling pathways associated with mitochondrial health. Studies have suggested that abnormalities in ND75 may be linked to several metabolic disorders and neurodegenerative diseases, such as Parkinson's and Alzheimer's, highlighting the importance of understanding its biological functions. The recombinant form of ND75 allows for detailed investigation of its structure and function, enabling researchers to elucidate its role in mitochondrial dynamics and explore its potential as a therapeutic target. Moreover, the development of ND75 recombinant protein opens avenues for high-throughput screening of small molecules that could modulate its activity, thus providing a promising approach for drug discovery aimed at treating diseases connected to mitochondrial dysfunction. As research progresses, the characterization of ND75 and its interactions with other mitochondrial proteins may offer insights into innovative strategies for managing mitochondrial-related disorders and enhancing cellular energy production.
