Analytical Data
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Gene name
TBX15
- Application
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Alternative Names
T-box transcription factor TBX14 ;T-box protein 14
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Species
Human
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Source
E. coli
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Tag
N- His-SUMO
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96SF7
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Expression Region
1-494aa
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Molecular Weight
70.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TBX15 is a member of the T-box family of transcription factors, which play crucial roles in embryonic development, cell differentiation, and various physiological processes. Research has highlighted TBX15's significant involvement in regulating fat tissue development and its potential links to obesity and metabolic disorders. Mutations and polymorphisms in the TBX15 gene have been associated with altered body mass index (BMI) and fat distribution, underscoring its importance in metabolic health. Recent studies have also suggested that TBX15 may have a role in skeletal development and influences the differentiation of mesenchymal stem cells into adipocytes and osteoblasts, providing insights into its dual role in bone and fat metabolism. Given these diverse functions, the study of recombinant TBX15 protein is imperative for understanding the molecular mechanisms underlying its action, which could pave the way for therapeutic interventions targeting metabolic diseases. The production of TBX15 as a recombinant protein facilitates detailed biochemical assays and characterizations of its interactions with other nuclear factors and cellular pathways, essential for comprehensive research in developmental biology and endocrinology. Understanding TBX15's functional roles at the protein level could potentially lead to novel strategies for treating conditions related to metabolism and development.
