Analytical Data
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Gene name
ITGAM
- Application
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Alternative Names
(CD11 antigen-like family member B)(CR-3 alpha chain)(Cell surface glycoprotein MAC-1 subunit alpha)(Leukocyte adhesion receptor MO1)(Neutrophil adherence receptor)(CD antigen CD11b)
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Species
Human
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Source
E. coli
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Tag
N- His-GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P11215
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Expression Region
46-150aa
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Molecular Weight
57.1 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ITGAM, also known as integrin alpha M, is a protein that plays a crucial role in the immune response by regulating the adhesion and migration of leukocytes. Its involvement in various inflammatory and autoimmune diseases, such as systemic lupus erythematosus and rheumatoid arthritis, has garnered significant research interest. Recent studies have aimed to explore the structural and functional properties of ITGAM, including its interactions with other proteins and cells within the immune system. The recombination of ITGAM protein has enabled researchers to delve deeper into its mechanisms of action, facilitating potential therapeutic applications. By producing recombinant ITGAM, scientists can investigate the protein's behavior in vitro, elucidating its role in immune cell signaling and migration. Furthermore, understanding how ITGAM contributes to disease pathology can unlock new avenues for targeted therapies, providing hope for patients with chronic inflammatory conditions. This ongoing research underscores the importance of ITGAM as a key player in immune regulation and highlights the potential for recombinant proteins in advancing our knowledge of immune-related disorders.
