Analytical Data
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Gene name
PHLDA1
- Application
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Alternative Names
Apoptosis-associated nuclear protein Proline- and glutamine-rich protein PHRIP, TDAG51
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Species
Human
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Source
E. coli
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Tag
N- His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8WV24
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Expression Region
1-401aa
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Molecular Weight
50.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PHLDA1, or Pleckstrin Homology-like Domain, Family A, Member 1, is a protein that has garnered significant attention due to its potential implications in various biological processes and diseases. Originally identified as a gene involved in the regulation of cell growth and apoptosis, PHLDA1 is known to interact with several key signaling pathways, particularly those related to cancer development and progression. Recent studies have highlighted its role in the modulation of cell survival, differentiation, and stress response, suggesting that it may act as a tumor suppressor in certain contexts. Additionally, PHLDA1's expression levels have been associated with various cancers, such as breast and colorectal cancer, indicating its potential use as a biomarker for diagnosis and prognosis. The pursuit of recombinant PHLDA1 proteins aims to facilitate a deeper understanding of its structure-function relationships and physiological roles. Through expression systems, researchers can produce this protein in sufficient quantities for functional assays, structural studies, and therapeutic applications. Ultimately, the exploration of PHLDA1's contributions to cellular mechanisms may pave the way for targeted therapies and novel diagnostic tools in oncology. The ongoing investigation of PHLDA1's functional properties and its interactions with other cellular components is critical for unraveling its potential as a target in cancer treatment and improving our grasp of tumor biology. As such, PHLDA1 research embodies a promising avenue in contemporary biomedical science.
