Analytical Data
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Gene name
DHRS9
- Application
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Alternative Names
DHRS9；RDH15；SDR9C4;Dehydrogenase/reductase SDR family member 9
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9BPW9
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Expression Region
18-319aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMRKGKL KIEDITDKYI FITGCDSGFG NLAARTFDKK GFHVIAACLT ESGSTALKAE TSERLRTVLL DVTDPENVKR TAQWVKNQVG EKGLWGLINN AGVPGVLAPT DWLTLEDYRE PIEVNLFGLI SVTLNMLPLV KKAQGRVINV SSVGGRLAIV GGGYTPSKYA VEGFNDSLRR DMKAFGVHVS CIEPGLFKTN LADPVKVIEK KLAIWEQLSP DIKQQYGEGY IEKSLDKLKG NKSYVNMDLS PVVECMDHAL TSLFPKTHYA AGKDAKIFWI PLSHMPAALQ DFLLLKQKAE LANPKAV
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Molecular Weight
36 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
DHRS9 (Dehydrogenase/Reductase 9) is a member of the short-chain dehydrogenase/reductase family, known for its involvement in the metabolism of retinoids and steroids. Recent studies have suggested that DHRS9 plays a crucial role in various physiological processes, including cell proliferation, differentiation, and apoptosis. Dysregulation of DHRS9 has been implicated in several diseases, including cancer, where altered retinoid metabolism can influence tumor progression and response to therapy. Furthermore, DHRS9 is believed to facilitate the conversion of polyunsaturated fatty acids into bioactive lipids, which are important for cellular signaling and maintaining metabolic homeostasis. As such, understanding the structure and function of DHRS9 through recombinant protein studies could provide valuable insights into its biological roles and potential therapeutic applications. Researchers aim to elucidate the enzymatic mechanisms, substrate specificity, and regulatory pathways associated with DHRS9 to explore its potential as a target for drug development. The production of recombinant DHRS9 allows for detailed biochemical characterization and the assessment of its function in various cellular contexts, thereby advancing our understanding of its contributions to health and disease.
