Analytical Data
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基因名
FCRL3
- Application
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别名
(FcR-like protein 3)(FcRL3)(Fc receptor homolog 3)(FcRH3)(IFGP family protein 3)(hIFGP3)(Immune receptor translocation-associated protein 3)(SH2 domain-containing phosphatase anchor protein 2)(CD antigen CD307c)
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种属
Human
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表达系统
E. coli
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q96P31
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表达区间
18-573aa
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分子量
67.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
FCRL3, or Fc receptor-like 3, is a protein belonging to the immunoglobulin superfamily, playing a crucial role in modulating immune responses. It is predominantly expressed on B cells, natural killer (NK) cells, and some T cells, making it integral to the adaptive and innate immune systems. Research has shown that FCRL3 is involved in various immune functions, including the regulation of antibody production, B cell activation, and interaction with other immune cells. Dysregulation of FCRL3 has been implicated in autoimmune diseases, such as systemic lupus erythematosus and rheumatoid arthritis, as well as in certain malignancies. The study of FCRL3 recombinant proteins is essential for understanding its functional mechanisms and therapeutic potential. By producing and characterizing FCRL3 recombinant proteins, researchers aim to elucidate its structural biology, functional pathways, and interactions with ligands or other proteins. This research could lead to novel strategies for manipulating immune responses, offering insights into the development of targeted therapies for autoimmune conditions and cancers. Thus, FCRL3 represents a promising target for further investigation in immunology and therapeutic applications.
