Analytical Data
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Gene name
FERMT2
- Application
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Alternative Names
(Kindlin-2)(Mitogen-inducible gene 2 protein)(MIG-2)(Pleckstrin homology domain-containing family C member 1)(PH domain-containing family C member 1)
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Species
Human
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Source
E. coli
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Tag
C- His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96AC1
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Expression Region
1-680aa
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Molecular Weight
83.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
FERMT2 (Fermitin Family Member 2) is a crucial protein that plays a significant role in cell adhesion and signaling pathways, primarily associated with the cytoskeleton. Recent studies have highlighted its involvement in various physiological processes, including cell proliferation, migration, and differentiation, which are essential in development and tissue homeostasis. Dysregulation of FERMT2 has been linked to several diseases, particularly certain types of cancer, where it may contribute to tumor progression and metastasis. The reconstitution of FERMT2 as a recombinant protein is essential for elucidating its structural and functional properties, allowing researchers to investigate its interactions with other proteins and its role in cellular mechanisms. Understanding the molecular biology of FERMT2 through recombinant protein studies may provide insights into its function in pathology and could open avenues for therapeutic interventions targeting its pathways. The availability of FERMT2 in a purified form facilitates high-throughput screening and functional assays, aimed at exploring its potential as a biomarker or therapeutic target in diseases characterized by aberrant cell signaling and adhesion. Thus, the research on FERMT2 recombinant protein is pivotal in advancing our understanding of its biological significance and therapeutic potential in the context of human health and disease.
