Analytical Data
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基因名
DDX19B
- Application
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别名
(DEAD box RNA helicase DEAD5)(DEAD box protein 19B)
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种属
Human
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表达系统
E. coli
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标签
N- His-SUMO
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UMR2
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表达区间
2-479aa
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分子量
66.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
DDX19B is a member of the DExD/H-box family of RNA helicases, which play crucial roles in various cellular processes, including RNA metabolism, gene expression regulation, and viral replication. The study of DDX19B has gained attention due to its involvement in essential biological functions and its potential implications in diseases, including cancer and viral infections. Research indicates that DDX19B is essential for the nuclear export of RNA and ribonucleoprotein complexes, thereby influencing the stability and translation of mRNAs. This protein has also been implicated in the modulation of several signaling pathways, suggesting its role as a regulatory factor in cellular homeostasis. Given the increasing discovery of DDX19B's multifaceted functions, recombinant DDX19B protein has become a valuable tool for exploring its molecular mechanisms, interactions with other proteins, and its potential as a therapeutic target. Furthermore, understanding DDX19B's function may lead to novel insights into the development of strategies against diseases where DDX19B is dysregulated. Consequently, the production and characterization of recombinant DDX19B protein facilitate detailed studies on its biochemical properties and biological significance, contributing to the broader understanding of RNA helicases in health and disease.
