Analytical Data
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基因名
FABP4
- Application
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别名
FABP4;Fatty acid-binding Protein. adipocyte
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P15090
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表达区间
1-132aa
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氨基酸序列
MCDAFVGTWK LVSSENFDDY MKEVGVGFAT RKVAGMAKPN MIISVNGDVI TIKSESTFKN TEISFILGQE FDEVTADDRK VKSTITLDGG VLVHVQKWDG KSTTIKRKRE DDKLVVECVM KGVTSTRVYE RA
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分子量
15 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Fatty acid-binding protein 4 (FABP4), also known as adipocyte FABP, plays a crucial role in lipid metabolism and is predominantly expressed in adipose tissue and macrophages. Its primary function involves the transport and binding of free fatty acids, which influences various metabolic processes, including insulin sensitivity, inflammation, and adipogenesis. In recent years, increasing evidence has highlighted the association of FABP4 with metabolic disorders such as obesity, type 2 diabetes, and cardiovascular diseases. Researchers have begun to explore FABP4 as a potential therapeutic target due to its pivotal role in these conditions. The production and study of recombinant FABP4 proteins have enabled scientists to investigate the protein's structural and functional properties in detail, as well as to assess its interactions with various ligands and cellular pathways. Understanding the mechanistic role of FABP4 in metabolic regulation could pave the way for novel interventions to combat obesity-related diseases. By utilizing recombinant DNA technology, scientists can produce adequate amounts of this protein for in vitro and in vivo studies, further elucidating its role in systemic metabolism and its potential as a biomarker for metabolic health.
