Analytical Data
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基因名
GPR61
- Application
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别名
GPR61; BALGR; GPCR3; G-protein coupled receptor 61; Biogenic amine receptor-like G-protein coupled receptor
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BZJ8
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表达区间
1-451aa
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氨基酸序列
MESSPIPQSSGNSSTLGRVPQTPGPSTASGVPEVGLRDVASESVALFFMLLLDLTAVAGNAAVMAVIAKTPALRKFVFVFHLCLVDLLAALTLMPLAMLSSSALFDHALFGEVACRLYLFLSVCFVSLAILSVSAINVERYYYVVHPMRYEVRMTLGLVASVLVGVWVKALAMASVPVLGRVSWEEGAPSVPPGCSLQWSHSAYCQLFVVVFAVLYFLLPLLLILVVYCSMFRVARVAAMQHGPLPTWMETPRQRSESLSSRSTMVTSSGAPQTTPHRTFGGGKAAVVLLAVGGQFLLCWLPYFSFHLYVALSAQPISTGQVESVVTWIGYFCFTSNPFFYGCLNRQIRGELSKQFVCFFKPAPEEELRLPSREGSIEENFLQFLQGTGCPSESWVSRPLPSPKQEPPAVDFRIPGQIAEETSEFLEQQLTSDIIMSDSYLRPAASPRLES
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分子量
49.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GPR61, an orphan G protein-coupled receptor (GPCR), has garnered attention in recent years due to its potential roles in various physiological processes and disease states. As a member of the class A GPCR family, GPR61 is characterized by its unique expression patterns in the brain and other tissues, suggesting involvement in neurotransmission and possibly other signaling pathways. Despite its discovery over two decades ago, the specific ligands and biological functions of GPR61 remain largely unidentified, making it a subject of intrigue in the field of molecular biology and pharmacology. Recent studies have indicated that GPR61 could be implicated in mood regulation, neuroprotection, and metabolic processes, highlighting the importance of elucidating its functional mechanisms. The development of recombinant GPR61 proteins facilitates the investigation of its structural characteristics and interactions with potential ligands, paving the way for therapeutic applications. Understanding GPR61's signaling pathways could also contribute to the broader comprehension of GPCRs and their roles in human health, potentially leading to novel strategies for treating psychiatric disorders, metabolic syndromes, and other related conditions. This highlights the significance of continued research on GPR61 as a promising target for drug discovery and therapeutic interventions.
