Recombinant Human GST Protein，His

Glutathione S-transferases (GSTs) are a family of enzymes that play a crucial role in cellular detoxification by catalyzing the conjugation of glutathione to a variety of xenobiotics and endogenous compounds. They are essential for protecting cells from oxidative stress and are involved in various metabolic pathways. Research on GSTs has expanded due to their significance in pharmacology, toxicology, and cancer biology, as alterations in GST expression can influence drug metabolism and susceptibility to toxins. Additionally, certain GST isoforms have been implicated in the development of multidrug resistance in cancer cells, making them potential targets for therapeutic intervention. The study of GST proteins, especially through methods such as recombinant protein expression and purification, allows scientists to investigate their structure-function relationships, enzymatic mechanisms, and potential as biomarkers or drug targets. Recent trends in GST research also focus on their roles in signaling pathways, the interaction with other proteins, and their involvement in various diseases, including inflammation and neurodegeneration. This growing body of knowledge highlights the importance of GSTs in both basic and applied biomedical research, underscoring the need for continued investigation into their biochemical properties and therapeutic applications.