Analytical Data
-
基因名
β-catenin
- Application
-
别名
β-catenin；
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
P35222
-
表达区间
1-781aa
-
氨基酸序列
MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKG NPEEEDVDTSQVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFP ETLDEGMQIPSTQFDAAHPTNVQRLAEPSQMLKHAVVNLINYQDDAELAT RAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVR TMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDS VLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDC LQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVC SSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEG LLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRT VLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHP PSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRR TSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFV QLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEG VATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDI GAQGEPLGYRQDDPSYRSFHSGGYGQDALGMDPMMEHEMGGHHPGADYPV DGLPDLGHAQDLMDGLPPGDSNQLAWFDTDL
-
分子量
112 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
β-Catenin is a dual-function protein that plays a significant role in cell adhesion and the Wnt signaling pathway, making it a critical component in various biological processes such as development, cell differentiation, and tumorigenesis. Research on β-catenin has gained momentum due to its involvement in various cancers, particularly colorectal cancer, where mutations in the β-catenin gene lead to its aberrant accumulation and activation of Wnt target genes. Understanding the structure and function of β-catenin is essential for elucidating its complex regulatory mechanisms and interactions within the cellular environment. The production of recombinant β-catenin protein has emerged as a vital tool in studying its properties and biological roles. By utilizing techniques such as recombinant DNA technology, researchers can produce β-catenin in substantial quantities for in vitro studies, enabling detailed analyses of its molecular interactions, post-translational modifications, and signaling pathways. Furthermore, recombinant β-catenin can be crucial for the development of targeted therapies and biomolecular probes that aim to modulate its activity in disease contexts. Through these investigations, insights into the dynamics of β-catenin can pave the way for innovative therapeutic strategies and improve our understanding of cancers and developmental disorders associated with β-catenin dysregulation. Overall, the study of recombinant β-catenin protein is an essential endeavor in both basic and translational research, contributing to the broader field of molecular biology and oncology.
