Analytical Data
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基因名
HOXB9
- Application
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别名
Homeo box 2E ; Homeo box B9 ; Homeobox B9; Homeobox protein Hox B9; Homeobox protein Hox-2.5; Homeobox protein Hox-2E; Homeobox protein Hox-B9; Hox 2.5; Hox 2E; HOX2; HOX2E; Hoxb9; HXB9_HUMAN; OTTHUMP00000216946; OTTHUMP00000243325
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P17482
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表达区间
1-250aa
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氨基酸序列
MSISGTLSSY YVDSIISHES EDAPPAKFPS GQYASSRQPG HAEHLEFPSC SFQPKAPVFG ASWAPLSPHA SGSLPSVYHP YIQPQGVPPA ESRYLRTWLE PAPRGEAAPG QGQAAVKAEP LLGAPGELLK QGTPEYSLET SAGREAVLSN QRPGYGDNKI CEGSEDKERP DQTNPSANWL HARSSRKKRC PYTKYQTLEL EKEFLFNMYL TRDRRHEVAR LLNLSERQVK IWFQNRRMKM KKMNKEQGKE
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分子量
28 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HOXB9 is a member of the Homeobox gene family, which plays a crucial role in regulating development and differentiation processes during embryogenesis. Recent studies have highlighted its significance in various biological contexts, including its involvement in the regulation of cell proliferation, apoptosis, and differentiation in both normal and pathological conditions. Abnormal expression or mutation of HOXB9 has been implicated in several cancers, including breast, colorectal, and prostate cancer, making it a potential biomarker for diagnosis and prognosis. The recombinant protein of HOXB9 is increasingly being utilized in research to discern its precise functions and interactions at the molecular level. By generating highly pure and functional HOXB9 recombinant proteins, researchers aim to study its biological activity and elucidate the underlying mechanisms by which it influences cellular behavior and disease progression. Additionally, understanding the structure-function relationship of HOXB9 can provide insights into the development of targeted therapeutic strategies aimed at modulating its activity in malignancies and other disorders linked to its dysregulation. Thus, the research on HOXB9 recombinant protein stands at the intersection of developmental biology and cancer research, promising to unveil novel therapeutic avenues and enhancing our understanding of gene regulation in health and disease.
