Analytical Data
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基因名
Cxcl17
- Application
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别名
Cxcl17;VCC1;C-X-C motif chemokine 17
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6UXB2
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表达区间
22-119aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MSSLNPGVAR GHRDRGQASR RWLQEGGQEC ECKDWFLRAP RRKFMTVSGL PKKQCPCDHF KGNVKKTRHQ RHHRKPNKHS RACQQFLKQC QLRSFALPL
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分子量
14 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CXCL17, a chemokine belonging to the CXC family, has garnered significant attention in recent years due to its potential role in immunological responses and its involvement in various diseases. Expressed in various tissues, CXCL17 is known for its ability to bind receptors on immune cells, influencing their migration and activation. Research has shown that CXCL17 plays a crucial role in inflammation, particularly in responses associated with respiratory and autoimmune diseases. Additionally, its expression has been linked to cancer progression, suggesting that it may have dual roles in promoting or inhibiting tumor development depending on the context. The study of recombinant CXCL17 protein has become vital for understanding its biological functions and mechanisms of action. Researchers aim to investigate its therapeutic potential, exploring how recombinant versions of the protein can be used in drug development for disease treatment. The ongoing exploration of CXCL17 not only enhances our comprehension of immune system regulation but also opens new avenues for targeted therapies in conditions where CXCL17 is dysregulated. Thus, the development and characterization of recombinant CXCL17 protein are essential for advancing both basic science and clinical applications in immunology and oncology.












