Cat: PA1000-1854

Recombinant Human LY6G6F Protein,His

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Analytical Data

  • Gene name

    LY6G6F

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    LY6G6F;C6orf21;G6F;LY6G6D;Lymphocyte antigen 6 complex locus Protein G6f

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q5SQ64

  • Expression Region

    17-235aa

  • AA Sequence

    MGSSHHHHHH SSGLVPRGSH MGSADNMQAI YVALGEAVEL PCPSPPTLHG DEHLSWFCSP AAGSFTTLVA QVQVGRPAPD PGKPGRESRL RLLGNYSLWL EGSKEEDAGR YWCAVLGQHH NYQNWRVYDV LVLKGSQLSA RAADGSPCNV LLCSVVPSRR MDSVTWQEGK GPVRGRVQSF WGSEAALLLV CPGEGLSEPR SRRPRIIRCL MTHNKGVSFS LAASIDASPA LCAPSTGWDM PW

  • Molecular Weight

    26 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

LY6G6F, a member of the LY6 family, has gained attention in immunology and cancer research due to its unique role in the immune system and its potential applications in therapeutic contexts. This glycosylphosphatidylinositol (GPI)-anchored protein is primarily expressed on immune cells, particularly T cells, where it influences cell activation and differentiation. Emerging studies suggest that LY6G6F might be crucial in modulating immune responses, as its expression correlates with various stages of T cell maturation and activation. Furthermore, its involvement in tumor immunity has sparked interest in understanding how LY6G6F can be exploited for cancer immunotherapy, potentially serving as a biomarker for T cell-based therapies or as a target for enhancing immune responses against tumors. The recombinant production of LY6G6F protein allows researchers to investigate its functional properties in vitro and in vivo, paving the way for novel therapeutic strategies. Analyzing the structure-function relationship of LY6G6F may provide insights into its mechanisms of action, further unraveling its role in both normal immune function and pathological conditions like cancer. As the field progresses, comprehending the implications of LY6G6F in immune regulation could lead to breakthroughs in overcoming immune evasion by tumors and improving patient outcomes in cancer therapy. Overall, the research on LY6G6F is poised to contribute significantly to the understanding of immune modulation and the development of innovative immunotherapeutic approaches.

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