Cat: PA2000-8861

Recombinant Human LCE2B Protein,GST

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Analytical Data

  • 基因名

    LCE2B

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    LCE2B; LEP10; SPRL1B; XP5Late cornified envelope protein 2B; Late envelope protein 10; Skin-specific protein Xp5; Small proline-rich-like epidermal differentiation complex protein 1B

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    GST-tag at N-terminal

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    O14633

  • 表达区间

    1-110aa

  • 氨基酸序列

    MSCQQNQQQCQPPPKCPPKCTPKCPPKCPPKCLPQCPAPCSPAVSSCCGPISGGCCGPSSGGCCNSGAGGCCLSHHRPRLFHRRRHQSPDCCESEPSGGSGCCHSSGGCC

  • 分子量

    38.5 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

The study of LCE2B recombinant protein is situated within the broader context of skin biology and immunology. LCE2B, part of the late cornified envelope (LCE) family, is implicated in the formation of the epidermal barrier and is crucial for maintaining skin homeostasis. Its expression is often upregulated in response to skin lesions and inflammatory conditions, making it a key player in the skin's defense mechanisms. Research has increasingly focused on the potential therapeutic applications of LCE2B in conditions such as psoriasis, eczema, and other skin disorders, where barrier dysfunction is evident. Recombinant technology allows for the production of LCE2B in controlled environments, facilitating the study of its structural and functional properties, as well as its interactions with other epidermal proteins. Understanding the precise role of LCE2B could yield insights into skin repair processes and open up avenues for innovative treatments aimed at enhancing skin barrier function or modulating inflammatory responses. As skin diseases significantly impact quality of life, the exploration of LCE2B offers hope for developing targeted therapies that effectively restore skin health and mitigate chronic dermatological conditions. Thus, research into LCE2B recombinant protein not only deepens our understanding of skin biology but also represents a critical step towards novel interventions in dermatological therapy.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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