Analytical Data
-
Gene name
CNP
- Application
-
Alternative Names
CNP；CNP2；C-type natriuretic peptide
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
P09543
-
Expression Region
1-421aa
-
AA Sequence
MNRGFSRKSHTFLPKIFFRKMSSSGAKDKPELQFPFLQDEDTVATLLECKTLFILRGLPGSGKSTLARVIVDKYRDGTKMVSADAYKITPGARGAFSEEYKRLDEDLAAYCRRRDIRILVLDDTNHERERLEQLFEMADQYQYQVVLVEPKTAWRLDCAQLKEKNQWQLSADDLKKLKPGLEKDFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRQFVPGDEPREKMDLVTYFGKRPPGVLHCTTKFCDYGKAPGAEEYAQQDVLKKSYSKAFTLTISALFVTPKTTGARVELSEQQLQLWPSDVDKLSPTDNLPRGSRAHITLGCAADVEAVQTGLDLLEILRQEKGGSRGEEVGELSRGKLYSLGNGRWMLTLAKNMEVRAIFTGYYGKGKPVPTQGSRKGGALQSCTII
-
Molecular Weight
47.5 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CNP (C-type natriuretic peptide) is a member of the natriuretic peptide family that plays a crucial role in cardiovascular physiology, particularly in regulating blood pressure and fluid balance. The interest in CNP recombinant protein research stems from its potential therapeutic applications in treating cardiovascular diseases, heart failure, and conditions associated with fluid overload. Recent studies have highlighted CNP's role in promoting vasodilation, inhibiting hypertrophy, and enhancing renal function, suggesting that it may offer protective effects against cardiovascular pathologies. Additionally, CNP is being investigated for its involvement in various cellular signaling pathways, which could lead to novel drug development strategies. Researchers are exploring the functional characteristics of CNP through recombinant protein techniques to better understand its mechanisms of action, optimize its pharmacological applications, and evaluate its efficacy in clinical settings. As a result, the study of CNP recombinant proteins is positioned at the forefront of cardiovascular and pharmacological research, aiming to provide innovative solutions for managing heart-related diseases.
