Analytical Data
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Gene name
LHX9
- Application
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Alternative Names
LHX 9; lhx9; LHX9_HUMAN; LIM homeobox 9; LIM homeobox 9 protein; LIM homeobox protein 9; LIM homeodomain type transcription factor; LIM homeodomain type transcription factor Lhx9; LIM/homeobox protein Lhx9
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9NQ69
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Expression Region
1-397aa
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AA Sequence
MEIVGCRAEDNSCPFRPPAMLFHGISGGHIQGIMEEMERRSKTEARLAKGAQLNGRDAGMPPLSPEKPALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFETLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENGGVDKADGTSLPAPPSADSGALTPPGTATTLTDLTNPTITVVTSVTSNMDSHESGSPSQTTLTNLF
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Molecular Weight
70.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
LHX9, a member of the LIM homeobox gene family, plays a crucial role in the development of various tissues, particularly in the central nervous system and the reproductive system. Research has indicated that LHX9 is essential for the proper specification of neuronal populations and the formation of brain structures, including the pituitary gland and hypothalamus, which are vital for hormonal regulation and overall physiological functioning. In recent years, studies have focused on the potential implications of LHX9 in developmental disorders and neuroendocrine dysfunctions. Given its involvement in critical pathways, the recombinant expression of LHX9 protein has become a focal point for studying its molecular functions and interactions. By producing LHX9 as a recombinant protein, researchers aim to elucidate its roles in cell differentiation, signaling pathways, and its potential connections to diseases. Understanding the structure and function of LHX9 at the molecular level could lead to therapeutic insights for conditions associated with its dysregulation, such as hypopituitarism and other neurodevelopmental disorders. Thus, the study of LHX9 recombinant protein not only enriches our knowledge of gene regulatory networks but also opens new avenues for clinical applications in regenerative medicine and targeted therapies.
