Analytical Data
-
基因名
GPR65
- Application
-
别名
GPR65；TDAG8；Psychosine receptor
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q8IYL9
-
表达区间
1-337aa
-
氨基酸序列
MNSTCIEEQHDLDHYLFPIVYIFVIIVSIPANIGSLCVSFLQAKKESELGIYLFSLSLSDLLYALTLPLWIDYTWNKDNWTFSPALCKGSAFLMYMNFYSSTAFLTCIAVDRYLAVVYPLKFFFLRTRRFALMVSLSIWILETIFNAVMLWEDETVVEYCDAEKSNFTLCYDKYPLEKWQINLNLFRTCTGYAIPLVTILICNRKVYQAVRHNKATENKEKKRIIKLLVSITVTFVLCFTPFHVMLLIRCILEHAVNFEDHSNSGKRTYTMYRITVALTSLNCVADPILYCFVTETGRYDMWNILKFCTGRCNTSQRQRKRILSVSTKDTMELEVLE
-
分子量
40.8 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GPR65, also known as the T cell-specific G protein-coupled receptor, is a member of the GPR family that plays a crucial role in regulating immune responses, particularly in T cell activation and differentiation. Research has indicated that GPR65 is involved in various pathological conditions, including autoimmune diseases and cancer. Activation of GPR65 can influence the production of cytokines and the signaling pathways that govern T cell proliferation and function, making it an important target for therapeutic interventions. The recombinant protein of GPR65 has been produced to facilitate studies on its biological function and signaling mechanisms. Such proteins can be utilized in the development of assays to investigate GPR65's role in immune regulation or to screen potential drug candidates that modulate its activity. Furthermore, understanding the structure and dynamics of the GPR65 protein through crystallography or NMR spectroscopy could provide insights into its interaction with ligands and downstream signaling partners. This research could ultimately contribute to identifying novel treatments for diseases characterized by dysregulated immune responses.
