Analytical Data
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Gene name
LEUTX
- Application
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Alternative Names
LEUTX；Paired-like homeodomain transcription factor LEUTX
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
A8MZ59
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Expression Region
1-168aa
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AA Sequence
MHPSLATMGK LASKLQLDLS VVKIWFKNQR AKWKRQQRQQ MQTRPSLGPA NQTTSVKKEE TPSAITTANI RPVSPGISDA NDHDLREPSG IKNPGGASAS ARVSSWDSQS YDIEQICLGA SNPPWASTLF EIDEFVKIYD LPGEDDTSSL NQYLFPVCLE YDQLQSSV
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Molecular Weight
22.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
LEUTX, a member of the oligophrenin family of proteins, has garnered significant interest in recent years due to its role in neurodevelopment and potential implications in various neurological disorders. Initially discovered in the context of early embryonic development, LEUTX is primarily expressed in the brain and plays a crucial role during neuronal differentiation and maturation. Mutations or dysregulation of LEUTX have been associated with developmental disorders and conditions such as autism spectrum disorders and schizophrenia, highlighting its importance in neural circuitry formation. Additionally, recent studies have indicated that LEUTX may interact with other key proteins associated with signaling pathways crucial for neuronal survival and growth. Understanding the structural characteristics and functional mechanisms of LEUTX through recombinant protein studies could provide valuable insights into its role in neurodevelopment and pathology. Moreover, leveraging recombinant DNA technology to produce LEUTX protein can facilitate detailed biochemical assays and functional analyses, paving the way for potential therapeutic strategies targeting LEUTX-related pathways in neurological diseases. Thus, the exploration of LEUTX as a recombinant protein represents a promising avenue for unraveling the complexities of brain development and its associated disorders.
