Analytical Data
-
Gene name
TP53TG5
- Application
-
Alternative Names
TP53TG5；C20orf10；TP53-target gene 5 Protein
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9Y2B4
-
Expression Region
1-290aa
-
AA Sequence
MSPSAKKRPK NSRVSKMQDE KLRDETEQPV SKVIERNRLR TVLKNLSLLK LLKSSNRRIQ ELHKLAKRCW HSLLSVPKIL RISSGENSAC NKTKQNNEEF QEIGCSEKEL KSKKLESTGD PKKKEYKEWK SQVQSGMRNK EKTSLAAMPR KEKHIEPEVP RTSRDDSLNP GVQGRQPLTE GPRVIFIKPY RNRTPMGHMK QLDVADQWIW FEGLPTRIHL PAPRVMCRSS TLRWVKRRCT RFCSASLEMP MWHPYKVDVT WTRARGASRG WRSRHQLKGR NGWRNSRVYK
-
Molecular Weight
34 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TP53TG5, also known as TP53 target gene 5, is a gene that plays a significant role in the regulation of cellular stress responses and is linked to the tumor suppressor gene TP53. The TP53 gene is crucial for maintaining genomic stability and preventing cancer, as it regulates the cell cycle, DNA repair, and apoptosis. The TP53TG5 protein has gained attention for its potential involvement in tumorigenesis and the cellular response to DNA damage. Recent studies have suggested that TP53TG5 may interact with various signaling pathways, influencing cell proliferation and survival. Understanding the functional mechanisms of TP53TG5 and its protein interactions is essential for elucidating its role in cancer biology. Researchers are particularly interested in its impact on the tumor microenvironment and therapeutic responses, as alterations in its expression levels could serve as potential biomarkers for cancer prognosis or treatment efficacy. By investigating TP53TG5 recombination proteins, scientists aim to uncover novel targets for anticancer therapies and enhance our understanding of TP53 pathway dynamics, ultimately contributing to advances in cancer diagnosis and treatment. This research is crucial, given the high prevalence of TP53 mutations in various cancers, and may lead to innovative therapeutic strategies aimed at reinstating TP53 function or targeting its downstream effectors.
