Cat: PA2000-9256

Recombinant Human MEF2BNB Protein,GST

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Analytical Data

  • 基因名

    MEF2BNB

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    MEF2B neighbor gene protein; mef2bnb; MF2NB_HUMAN; Protein MEF2BNB

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    GST-tag at N-terminal

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q96FH0

  • 表达区间

    1-119aa

  • 氨基酸序列

    MEEPEMQLKG KKVTDKFTES VYVLANEPSV ALYRLQEHVR RSLPELAQHK ADMQRWEEQS QGAIYTVEYA CSAVKNLVDS SVYFRSVEGL LKQAISIRDH MNASAQGHSP EEPPPPSSA

  • 分子量

    13,4 KDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

The MEF2B gene, part of the myocyte enhancer factor 2 (MEF2) family, plays a crucial role in regulating gene expression during myogenesis and neuronal development. Recent studies have highlighted its involvement in various cellular processes, including differentiation, apoptosis, and stress responses, making it a significant focus in understanding muscle and neuronal pathologies. The MEF2B protein is known to undergo post-translational modifications that can influence its activity and stability, contributing to the dynamic regulation of gene expression. Research has revealed that mutations in MEF2B are associated with several disorders, including cardiomyopathies and neurodevelopmental disorders, indicating its importance in both muscle and brain function. To further investigate the functional mechanisms of MEF2B and develop therapeutic strategies, researchers have begun to focus on the production of recombinant MEF2B proteins. By utilizing various expression systems, scientists aim to create high-purity MEF2B variants for biochemical and structural studies. This includes examining how different post-translational modifications affect the protein's interaction with other cellular factors, as well as its role in transcriptional regulation. The development of recombinant MEF2B proteins can facilitate drug discovery, biomarker identification, and the design of novel interventions for diseases linked to MEF2B dysregulation, thus holding promise for advancing our understanding of its biological functions and therapeutic potential in related disorders.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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