Analytical Data
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基因名
PTGDR
- Application
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别名
PTGDR；Prostaglandin D2 receptor
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q13258
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表达区间
1-359aa
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氨基酸序列
MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSVFYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSSTLQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPGTWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSCTRDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTSEEAEDLRALRFLSVISIVDPWIFIIFRSPVFRIFFHKIFIRPLRYRSRCSNSTNMESSL
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分子量
40.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PTGDR (Prostaglandin D2 Receptor) is a G-protein-coupled receptor that plays a pivotal role in mediating the effects of prostaglandin D2, particularly in the context of allergic responses, inflammation, and regulation of sleep. The interest in PTGDR research has grown due to its potential implications in various pathological conditions, including asthma, sleep disorders, and neurodegenerative diseases. Researchers have increasingly focused on the structural and functional aspects of PTGDR to elucidate its signaling mechanisms and interaction with ligands. The development of recombinant PTGDR proteins has enabled the exploration of its pharmacological properties and has provided insights into designing specific agonists or antagonists that could modulate its activity. Furthermore, understanding the molecular dynamics and conformational changes of PTGDR upon ligand binding is essential for drug discovery efforts aimed at addressing the therapeutic challenges associated with PTGDR-related diseases. As the field progresses, continued research into the biophysical properties and biological functions of PTGDR will pave the way for novel therapeutic strategies targeting this receptor, potentially leading to significant advancements in treating various inflammatory and allergic conditions.
