Analytical Data
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基因名
FOXG1
- Application
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别名
FOXG1；FKH2；FKHL1；FKHL2；Forkhead box Protein G1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P55316
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表达区间
1-489aa
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氨基酸序列
MLDMGDRKEVKMIPKSSFSINSLVPEAVQNDNHHASHGHHNSHHPQHHHHHHHHHHHPPPPAPQPPPPPQQQQPPPPPPPAPQPPQTRGAPAADDDKGPQQLLLPPPPPPPPAAALDGAKADGLGGKGEPGGGPGELAPVGPDEKEKGAGAGGEEKKGAGEGGKDGEGGKEGEKKNGKYEKPPFSYNALIMMAIRQSPEKRLTLNGIYEFIMKNFPYYRENKQGWQNSIRHNLSLNKCFVKVPRHYDDPGKGNYWMLDPSSDDVFIGGTTGKLRRRSTTSRAKLAFKRGARLTSTGLTFMDRAGSLYWPMSPFLSLHHPRASSTLSYNGTTSAYPSHPMPYSSVLTQNSLGNNHSFSTANGLSVDRLVNGEIPYATHHLTAAALAASVPCGLSVPCSGTYSLNPCSVNLLAGQTSYFFPHVPHPSMTSQSSTSMSARAASSSTSPQAPSTLPCESLRPSLPSFTTGLSGGLSDYFTHQNQGSSSNPLIH
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分子量
53.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
FOXG1 is a transcription factor that plays a crucial role in brain development, particularly in the regulation of neural stem cell proliferation and differentiation. Mutations or deletions in the FOXG1 gene have been linked to developmental disorders, including FOXG1 syndrome, which is characterized by severe neurodevelopmental delays, intellectual disabilities, and impaired motor skills. As a result, understanding the function and mechanisms of FOXG1 is critical for uncovering the etiology of these disorders and developing potential therapeutic strategies. Research on FOXG1 recombinant protein focuses on its interactions with other cellular pathways involved in neural development and its role in gene regulation. By studying FOXG1 in vitro and in vivo using recombinant protein approaches, scientists aim to elucidate its specific molecular mechanisms, characterize its protein interactions, and determine how alterations in FOXG1 activity can lead to the clinical manifestations observed in affected individuals. This research not only provides insights into the fundamental biology of brain development but also holds promise for identifying novel treatment approaches for FOXG1-related conditions.
