Analytical Data
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基因名
MRPL16
- Application
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别名
39S ribosomal protein L16; 39S ribosomal protein L16 mitochondrial; L16mt; mitochondrial; Mitochondrial ribosomal protein L16; MRP-L16; Mrpl16; PNAS 111; RM16_HUMAN
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NX20
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表达区间
37-251 aa
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氨基酸序列
PSFE DVSIPEKPKL RFIERAPLVP KVRREPKNLS DIRGPSTEAT EFTEGNFAIL ALGGGYLHWG HFEMMRLTIN RSMDPKNMFA IWRVPAPFKP ITRKSVGHRM GGGKGAIDHY VTPVKAGRLV VEMGGRCEFE EVQGFLDQVA HKLPFAAKAV SRGTLEKMRK DQEERERNNQ NPWTFERIAT ANMLGIRKVL SPYDLTHKGK YWGKFYMPKR V
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分子量
28.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MRPL16, a mitochondrial ribosomal protein, has garnered significant attention in recent years due to its crucial role in mitochondrial translation and cellular metabolism. Mitochondria, often referred to as the powerhouse of the cell, are essential for ATP production and play a pivotal role in various metabolic pathways. Understanding the function of mitochondrial ribosomal proteins like MRPL16 is vital as they are integral to the synthesis of mitochondrial-encoded proteins, which are essential for the proper functioning of the oxidative phosphorylation system. Dysregulation or mutations in MRPL16 can lead to mitochondrial dysfunction, which is linked to a range of diseases, including mitochondrial myopathies and metabolic syndromes. Recent studies suggest that MRPL16 may also participate in the regulation of mitochondrial biogenesis and apoptosis, highlighting its potential involvement in aging and neurodegenerative diseases. Therefore, elucidating the structure, function, and regulatory mechanisms of MRPL16 not only deepens our understanding of mitochondrial biology but also opens avenues for therapeutic intervention in various mitochondrial-related disorders. As research continues to uncover the multifaceted roles of MRPL16, it holds promise as a potential biomarker or target for treatment strategies aimed at enhancing mitochondrial function and addressing metabolic diseases.
