Analytical Data
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Gene name
PGM2
- Application
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Alternative Names
PGM2；Phosphopentomutase
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96G03
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Expression Region
1-612aa
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AA Sequence
MGSSHHHHHHSSGLVPRGSHMGSMAAPEGSGLGEDARLDQETAQWLRWDK NSLTLEAVKRLIAEGNKEELRKCFGARMEFGTAGLRAAMGPGISRMNDLT IIQTTQGFCRYLEKQFSDLKQKGIVISFDARAHPSSGGSSRRFARLAATT FISQGIPVYLFSDITPTPFVPFTVSHLKLCAGIMITASHNPKQDNGYKVY WDNGAQIISPHDKGISQAIEENLEPWPQAWDDSLIDSSPLLHNPSASINN DYFEDLKKYCFHRSVNRETKVKFVHTSVHGVGHSFVQSAFKAFDLVPPEA VPEQKDPDPEFPTVKYPNPEEGKGVLTLSFALADKTKARIVLANDPDADR LAVAEKQDSGEWRVFSGNELGALLGWWLFTSWKEKNQDRSALKDTYMLSS TVSSKILRAIALKEGFHFEETLTGFKWMGNRAKQLIDQGKTVLFAFEEAI GYMCCPFVLDKDGVSAAVISAELASFLATKNLSLSQQLKAIYVEYGYHIT KASYFICHDQETIKKLFENLRNYDGKNNYPKACGKFEISAIRDLTTGYDD SQPDKKAVLPTSKSSQMITFTFANGGVATMRTSGTEPKIKYYAELCAPPG NSDPEQLKKELNELVSAIEEHFFQPQKYNLQPKAD
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Molecular Weight
71 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PGM2 (Phosphoglycerate Mutase 2) is an enzyme involved in the glycolytic pathway, facilitating the conversion of 2-phosphoglycerate to 3-phosphoglycerate. This enzyme is crucial for cellular energy metabolism and is implicated in various physiological processes. Research into PGM2 has gained traction due to its potential role in metabolic disorders, cancer progression, and cellular signaling pathways. Variations in PGM2 expression and activity can disrupt metabolic homeostasis, leading to diseases. In particular, overexpression of PGM2 has been linked with tumorigenesis, suggesting its importance as a therapeutic target. Studies have focused on the structural and functional aspects of PGM2, utilizing recombinant protein techniques to elucidate its enzymatic mechanisms, regulation, and interactions with other metabolic pathways. Understanding the role of PGM2 in disease contexts not only provides insights into metabolic dysfunctions but also opens avenues for novel interventions and the development of specific inhibitors or modulators as potential therapeutic strategies. Thus, ongoing research on PGM2 is critical for advancing our knowledge of cellular metabolism and its implications in health and disease.
