Analytical Data
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基因名
PTTG1
- Application
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别名
PTTG1;EAP1;PTTG;TUTR1;Securin
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O95997
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表达区间
2-202aa
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氨基酸序列
ATLIYVDKE NGEPGTRVVA KDGLKLGSGP SIKALDGRSQ VSTPRFGKTF DAPPALPKAT RKALGTVNRA TEKSVKTKGP LKQKQPSFSA KKMTEKTVKA KSSVPASDDA YPEIEKFFPF NPLDFESFDL PEEHQIAHLP LSGVPLMILD EERELEKLFQ LGPPSPVKMP SPPWESNLLQ SPSSILSTLD VELPPVCCDI DI
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PTTG1 (pituitary tumor-transforming gene 1) is a multifunctional protein initially identified for its role in pituitary tumorigenesis. It encodes a protein that plays a critical role in cell cycle regulation, particularly in the transition from the G2 phase to mitosis. Overexpression of PTTG1 has been implicated in various tumors, suggesting its potential as a biomarker for cancer diagnosis and prognosis. Recent studies have focused on the recombinant expression of PTTG1 to explore its functional properties and interactions with other cellular pathways. Researchers aim to produce high-quality recombinant PTTG1 protein to investigate its structural characteristics, biological activity, and potential involvement in tumorigenic processes. The generation of recombinant PTTG1 also facilitates the study of its interaction with specific receptors, aiding in the understanding of its role in tumor development and progression. Additionally, this research may pave the way for novel therapeutic strategies targeting PTTG1, offering hope for more effective cancer treatments. Understanding the mechanisms by which PTTG1 contributes to tumor biology is essential for developing targeted interventions that could improve patient outcomes in cancers associated with this protein.
