Analytical Data
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基因名
NHLRC2
- Application
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别名
1200003G01Rik; DKFZp779F115; FLJ20147; FLJ25621; FLJ33312; MGC45492; NHL repeat containing 2; NHL repeat-containing protein 2; NHLC2_HUMAN; NHLRC2; Novel NHL repeat domain containing protein; OTTHUMP00000020518
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8NBF2
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表达区间
1-726 aa
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氨基酸序列
MAAPGGRGRS LSGLLPAQTS LEYALLDAVT QQEKDSLVYQ YLQKVDGWEQ DLSVPEFPEG LEWLNTEEPI SVYKDLCGKI VVLDFFTYCC INCIHLLPDL HALEHTYSDK DGLLIIGVHS AKFPNEKVLD NIKSAVLRYN ITHPMVNDAD ASLWQELEVS CWPTLVILGP RGNMLFSLIG EGHKDKLFLY TSIALKYYKD RGQIRDNKIG IKLYKDSLPP SPLLFPGKVT VDQVTDRLVI ADTGHHRILV VWKNGQIQYS IGGPNPGRKD GIFSESTFNS PQGVAIMNNI IYVADTENHL IRKIDLEAEK VSTVAGIGIQ GTDKEGGAKG EQQPISSPWD VVFGTSGSEV QRGDILWIAM AGTHQIWALL LDSGKLPKKN ELTKGTCLRF AGSGNEENRN NAYPHKAGFA QPSGLSLASE DPWSCLFVAD SESSTVRTVS LKDGAVKHLV GGERDPMNLF AFGDVDGVGI NAKLQHPLGV TWDKKRNLLY VADSYNHKIK VVDPKTKNCT TLAGTGDTNN VTSSSFTEST FNEPGGLCIG ENGELLYVAD TNNHQIKVMD LETKMVSVLP IFRSENAVVD GPFLVEKQKT LPKLPKSAPS IRLSPVTACA GQTLQFKLRL DLPSGSKLTE GVSSCWFLTA EGNEWLLQGQ IAAGDIENIS SQPTISLQIP DDCLSLEAIV SVSVFLYYCS ADSSACMMKA ILFSQPLQIT DTQQGCIAPV ELRYVF
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分子量
79.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
NHLRC2, a member of the NCL-1/Hca-1/LIS1 (NHL) family of proteins, has garnered attention for its potential roles in various cellular processes, including cell proliferation, differentiation, and apoptosis. This protein contains NHL repeats, which are known to facilitate protein-protein interactions, suggesting that NHLRC2 may serve as a crucial regulatory molecule in signaling pathways. Recent studies have implicated NHLRC2 in several biological functions, such as modulating immune responses and influencing neuronal development. Given its diverse roles, there is growing interest in understanding how NHLRC2 contributes to pathophysiological conditions, including cancer and neurodegenerative diseases. Researchers have begun to investigate the functional domains of NHLRC2 and its interactions with other key proteins, aiming to elucidate its mechanism of action within the cell. The recombinant expression of NHLRC2 provides a valuable avenue for characterizing its biophysical properties and understanding its biological functions in greater detail. By harnessing techniques in molecular biology and protein engineering, scientists hope to uncover the therapeutic potential of NHLRC2, paving the way for innovative strategies in disease treatment and intervention. Thus, studying NHLRC2 and its recombinant forms represents a significant step toward unveiling its contributions to health and disease.
