Analytical Data
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Gene name
NHLRC3
- Application
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Alternative Names
NHLRC3NHL repeat-containing protein 3
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q5JS37
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Expression Region
26-347 aa
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AA Sequence
GSPVL RNFTFAVSWR TEKILYRLDV GWPKHPEYFT GTTFCVAVDS LNGLVYIGQR GDNIPKILVF TEDGYFLRAW NYTVDTPHGI FAASTLYEQS VWITDVGSGF FGHTVKKYSS FGDLVQVLGT PGKKGTSLNP LQFDNPAELY VEDTGDIYIV DGDGGLNNRL IKLSQDFMIL WLHGENGTGP AKFNIPHSVT LDSAGRVWVA DRGNKRIQVF DKDTGEWLGA WNNCFTEEGP SSVRFTPDGK YLIVAQLNLS RLSVVAAPPV GSIGECSVIS TIQLADQVLP HLLEVDRKTG AVYVAEIGAK QVQKYVPLNS YVPSFGS
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Molecular Weight
38.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
NHLRC3, an important member of the NHL (NCL-2, HEN1, and LRP) family of proteins, has garnered significant attention in the context of various biological processes and disease mechanisms due to its involvement in gene regulation and cellular stress responses. Initial studies indicated that NHLRC3 plays a pivotal role in cellular homeostasis, protein stability, and the modulation of immune responses. Its expression patterns are notably altered in several pathological conditions, including cancer and neurodegenerative disorders, highlighting its potential as a biomarker and therapeutic target. Recent research has focused on the molecular mechanisms underlying NHLRC3's function, revealing its impact on key signaling pathways and interaction with other proteins. Given its dual role in maintaining cell integrity while also participating in the regulation of stress responses, NHLRC3 presents a compelling subject for further investigation. Understanding the structure-function relationship of NHLRC3, particularly through the development of recombinant protein variants, could provide valuable insights into its biological activity and open avenues for the development of novel therapeutic strategies. Thus, the study of NHLRC3 recombinant proteins is poised to contribute significantly to our understanding of cellular processes and their implications in health and disease.
