Analytical Data
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基因名
ADAM11
- Application
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别名
ADAM11; MDC; Disintegrin and metalloProteinase domain-containing Protein 11
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O75078
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表达区间
25-93aa
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氨基酸序列
MGSSHHHHHHSSGLVPRGSHMGPYGANMEDSVCCRDYVRYRLPLRVVKHFYWTSDSCPRPGVVLLTFRDKEICADPRVPWVKMILNKLSQ
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分子量
10.3 KDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ADAM11 (A Disintegrin and Metalloproteinase 11) is a member of the ADAM family of proteins, which are characterized by their disintegrin and metalloproteinase domains. These proteins play crucial roles in various biological processes, including cell adhesion, migration, and proteolytic cleavage of extracellular matrix components. Research has indicated that ADAM11 is implicated in key physiological and pathological processes, including neurogenesis, synaptic plasticity, and certain cancers. The significance of ADAM11 in human health has prompted investigations into its structure and function, particularly its role in cell signaling pathways. Recombination technologies have enabled the production of recombinant ADAM11 protein, facilitating detailed studies of its activity, interactions with other proteins, and potential therapeutic applications. Understanding the biochemical properties of this protein at the molecular level could illuminate its function in normal biology as well as its role in disease progression. Moreover, recombinant ADAM11 could serve as a valuable tool for drug development and biomarker identification in disease contexts, particularly in neurological and oncological research. Overall, the study of recombinant ADAM11 is pivotal for advancing our comprehension of its biological roles and therapeutic potential.
