Analytical Data
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Gene name
STX1A
- Application
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Alternative Names
STX1A；STX1；Syntaxin-1A
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q16623
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Expression Region
1-265aa
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AA Sequence
MKDRTQELRTAKDSDDDDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAEN VEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSI EQEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQ RQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSISKQALSEIETRHS EIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSD TKKAVKYQSKARRKK
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Molecular Weight
31 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
STX1A (Syntaxin 1A) is a member of the syntaxin family of proteins, which play a crucial role in the process of synaptic vesicle exocytosis, a fundamental mechanism for neurotransmitter release in neuronal communication. The proper functioning of STX1A is essential for the regulation of synaptic transmission, influencing various physiological processes, including learning and memory. Dysregulation or mutations in STX1A have been implicated in several neurological disorders and synaptic dysfunctions, making it a significant target for research. Studies have shown that STX1A interacts with other proteins in the SNARE complex, facilitating the fusion of synaptic vesicles with the presynaptic membrane. The recombinant expression of STX1A protein allows for detailed investigation of its functional properties, structural analysis, and interaction with other molecular partners. Understanding the role of STX1A through recombinant protein studies could provide insights into the molecular mechanisms underlying neuronal signaling and may aid in the development of therapeutic strategies for related neuropsychiatric and neurodegenerative conditions. Overall, research on STX1A recombinant proteins holds promise for enhancing our comprehension of synaptic biology and the intricate pathways of neurotransmission.
