Cat: PA2000-5727

Recombinant Human AXUD1 Protein,GST

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Analytical Data

  • Gene name

    AXUD1

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    Csrnp1; Axud1; Taip3Cysteine/serine-rich nuclear Protein 1; CSRNP-1; Axin-1 up-regulated gene 1 Protein

  • Species

    Human

  • Source

    E. coli

  • Tag

    GST-tag at N-terminal

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q96S65

  • Expression Region

    1-589aa

  • AA Sequence

    MTGLLKRKFDQLDEDNSSVSSSSSSSGCQSRSCSPSSSVSRAWDSEEEGPWDQMPLPDRDFCGPRSFTPLSILKRARRERPGRVAFDGITVFYFPRCQGFTSVPSRGGCTLGMALRHSACRRFSLAEFAQEQARARHEKLRQRLKEEKLEMLQWKLSAAGVPQAEAGLPPVVDAIDDASVEEDLAVAVAGGRLEEVSFLQPYPARRRRALLRASGVRRIDREEKRELQALRQSREDCGCHCDRICDPETCSCSLAGIKCQMDHTAFPCGCCREGCENPMGRVEFNQARVQTHFIHTLTRLQLEQEAESFRELEAPAQGSPPSPGEEALVPTFPLAKPPMNNELGDNSCSSDMTDSSTASSSASGTSEAPDCPTHPGLPGPGFQPGVDDDSLARILSFSDSDFGGEEEEEEEGSVGNLDNLSCFHPADIFGTSDPGGLASWTHSYSGCSFTSGILDENANLDASCFLNGGLEGSREGSLPGTSVPPSMDAGRSSSVDLSLSSCDSFELLQALPDYSLGPHYTSQKVSDSLDNIEAPHFPLPGLSPPGDASSCFLESLMGFSEPAAEALDPFIDSQFEDTVPASLMEPVPV

  • Molecular Weight

    90.53 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

AXUD1 (AXin Up-Regulated 1) is a protein that has garnered interest in the field of molecular biology and cancer research due to its potential role in the regulation of cell proliferation and apoptosis. Recent studies have suggested that AXUD1 may function as a significant mediator in the Wnt signaling pathway, which is crucial for various developmental processes and is often dysregulated in cancer. The overexpression of AXUD1 has been linked to poor prognosis in several cancer types, indicating its possible use as a biomarker for cancer progression. Furthermore, AXUD1 is believed to interact with key proteins involved in cellular signaling and stress responses, highlighting its importance in maintaining cellular homeostasis. Given its implicated roles in tumor biology, the investigation of AXUD1 as a therapeutic target is gaining momentum. Researchers are exploring its potential to be engineered as a recombinant protein to elucidate its biological functions and interactions, which could provide valuable insights for the development of novel cancer therapies. Understanding the molecular mechanisms by which AXUD1 operates is crucial for exploiting its potential in clinical applications. As such, the study of AXUD1 represents a promising avenue for advancing our knowledge of cancer biology and developing targeted treatment strategies.

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