Analytical Data
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基因名
PIGP
- Application
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别名
PIGP; DCRC; DSCR5; DSCRC; NPD010; Phosphatidylinositol N-acetylglucosaminyltransferase subunit P; Down syndrome critical region protein 5; Down syndrome critical region protein C; Phosphatidylinositol-glycan biosynthesis class P protein; PIG-P
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P57054
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表达区间
1-134 aa
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氨基酸序列
MVENSPSPLPERAIYGFVLFLSSQFGFILYLVWAFIPESWLNSLGLTYWPQKYWAVALPVYLLIAIVIGYVLLFGINMMSTSPLDSIHTITDNYAKNQQQKKYQEEAIPALRDISISEVNQMFFLAAKELYTKN
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分子量
40.37 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PIGP, or Phosphatidylinositol Glycan Anchor Biosynthesis Class P, is a key protein involved in the biosynthesis of glycosylphosphatidylinositol (GPI) anchors, which are important for the attachment of proteins to cell membranes. GPI-anchored proteins play crucial roles in various biological processes, including cell signaling, adhesion, and protein localization. Mutations or dysfunctions in the genes responsible for GPI anchor biosynthesis can lead to a range of human diseases, including neurodegenerative disorders and developmental syndromes. Research on recombinant PIGP is essential to elucidate its function and the mechanisms underlying GPI anchor biosynthesis. By producing PIGP as a recombinant protein, scientists aim to investigate its enzymatic activity, identify potential interactions with other proteins, and explore its regulatory role in GPI anchor formation. This research not only enhances our understanding of fundamental biological processes but also holds potential implications for therapeutic strategies targeting diseases related to GPI anchor deficiencies. Additionally, the study of PIGP and its pathway may contribute to advancements in biotechnology, including the development of novel drug delivery systems that utilize GPI anchors for enhanced stability and efficacy.
