Analytical Data
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基因名
BRP44
- Application
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别名
MPC2; BRP44; Mitochondrial pyruvate carrier 2; Brain Protein 44
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O95563
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表达区间
1-127aa
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氨基酸序列
MSAAGARGLRATYHRLLDKVELMLPEKLRPLYNHPAGPRTVFFWAPIMKWGLVCAGLADMARPAEKLSTAQSAVLMATGFIWSRYSLVIIPKNWSLFAVNFFVGAAGASQLFRIWRYNQELKAKAHK
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分子量
40.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
BRP44 (Bromodomain and PHD finger-containing protein 44) is an important protein that has garnered significant attention due to its potential roles in various biological processes and diseases. Initially identified as a component involved in the regulation of gene expression, BRP44 is characterized by the presence of both bromodomain and PHD finger motifs, indicating its involvement in chromatin remodeling and transcriptional regulation. Research has shown that BRP44 plays a crucial role in cellular differentiation and development, particularly in the context of stem cell biology and cancer. Abnormal expression or mutation of BRP44 has been linked to several malignancies, suggesting that it may act as a potential biomarker or therapeutic target. Furthermore, the protein's interactions with other chromatin-modifying complexes highlight its importance in maintaining epigenetic homeostasis. Understanding the structure, function, and regulatory mechanisms of BRP44 through the study of its recombinant protein could offer valuable insights into its role in normal physiology and pathology. As research progresses, elucidating the molecular pathways mediated by BRP44 may open avenues for novel therapeutic interventions aimed at diseases where BRP44's dysregulation is a contributing factor. Overall, the exploration of BRP44 recombinant protein not only enhances our understanding of epigenetic regulation but also underscores its significance in the context of precision medicine and targeted therapies.












