Analytical Data
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基因名
AZU1
- Application
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别名
AZU1；Azurocidin
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P20160
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表达区间
27-250aa
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氨基酸序列
IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGV STVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREAN LTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTP EDQCRPNNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRGP DFFTRVALFRDWIDGVLNNPGPGP
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分子量
26 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
AZU1, also known as azurocidin 1, is a member of the defensin family of antimicrobial proteins primarily expressed in neutrophils. Its primary role is to play a crucial part in the innate immune response by displaying antibacterial and antifungal activities. The interest in AZU1 recombinant proteins stems from the growing need to understand its structure-function relationship and therapeutic potential in infectious diseases and inflammation. Research has shown that AZU1 not only contributes to pathogen clearance but also modulates inflammatory responses, making it a potential target for developing novel immunotherapeutic strategies. Furthermore, recombinant production of AZU1 allows for detailed biochemical studies, enabling researchers to explore its mechanism of action and interactions with microbial pathogens. Understanding AZU1's role could lead to breakthroughs in enhancing immune responses or mitigating excessive inflammation, thus providing a valuable avenue for therapeutic innovation in treating various diseases.
