Analytical Data
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基因名
CDCA5
- Application
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别名
CDCA5; CDCA5_HUMAN; Cell division cycle associated Protein 5; Cell division cycle-associated Protein 5; MGC16386; p35; Sororin
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q96FF9
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表达区间
1-252aa
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氨基酸序列
MSGRRTRSGGAAQRSGPRAPSPTKPLRRSQRKSGSELPSILPEIWPKTPSAAAVRKPIVLKRIVAHAVEVPAVQSPRRSPRISFFLEKENEPPGRELTKEDLFKTHSVPATPTSTPVPNPEAESSSKEGELDARDLEMSKKVRRSYSRLETLGSASTSTPGRRSCFGFEGLLGAEDLSGVSPVVCSKLTEVPRVCAKPWAPDMTLPGISPPPEKQKRKKKKMPEILKTELDEWAAAMNAEFEAAEQFDLLVE
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分子量
54 KDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CDCA5 (Cell Division Cycle Associated 5) is a crucial protein involved in the regulation of cell division, particularly during the processes of mitosis and chromosome segregation. Research on CDCA5 has garnered interest due to its role in maintaining genomic stability and its potential implications in cancer biology. Abnormal expression or function of CDCA5 has been linked to various malignancies, suggesting that it may act as an oncogene. The study of CDCA5 recombinant proteins is pivotal for elucidating its structure-function relationships and interactions with other mitotic regulators. By producing CDCA5 in a recombinant form, researchers can investigate its biochemical properties, cellular localization, and the mechanisms by which it influences cell cycle progression. Understanding CDCA5's role in the cell cycle could provide insights into novel therapeutic targets for cancer treatment, making it a significant focus in cancer research. Overall, the exploration of CDCA5 and its recombinant protein may contribute to the development of innovative strategies to combat cell division-related diseases, offering a promising avenue for future research and therapeutic advancements.
